cGMP Tools

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Arginase

sGC Inhibitors

sGC Activators (I)

sGC Activators (II)

PKG Inhibitors






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Created by Dr. Luis Agulló (last update on 12-6-2007)



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1. Modulation of the Arginine uptake

2. Modulation of Arginase

3. Modulation of Nitric Oxide Synthases

3.1. Non-selective Inhibitors

3.2. Isozyme Selective Inhibitors

4. Tools to Study the Role of Guanylyl Cyclases

4.1. Inhibitors of Soluble Guanylyl Cyclase

4.2. NO-donors

4.3. Activators of Soluble Guanylyl Cyclase

4.3.1. Heme-dependent sGC Activators

4.3.2. Heme-independent sGC Activators

4.4. Inhibitors of Particulate Guanylyl Cyclase

4.5. Activators of Particulate Guanylyl Cyclase

4.6. Antibodies

5. Modulation of cyclic Nucleotide Phosphodiesterases

5.1. Inhibitors of cGMP Phosphodiesterases (PDE5, PDE6 and PDE9)

5.2. Inhibitors of cAMP and cGMP phosphodiesterases (PDE1 and PDE2)

5.3. Antibodies

6. cGMP Membrane Transport (cGMP Efflux)

7. Modulation of Protein Kinase G

7.1. Inhibitors of PKG

7.2. Activators of PKG






The information included here is not influenced by any commercial interest and it is only based on scientific publications, personal communications (author cited) or in our own experience. Please, if you have experience with some drug or antibody, contact with us and your information will be included here with your name and affiliation. Thank you.


Note 1: We cannot guarantee the absence of errors in the data provided here. Please, consult the original sources and contact with me if you detect any mistake!

Note 2: The absence of an indication of undesirable effects for some drugs is not a proof of their specificity!

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