Cyclic GMP: Pharmacological Tools

1. Modulation of the Arginine uptake

2. Modulation of Arginase

3. Modulation of Nitric Oxide Synthases

3.1. Non-selective Inhibitors

3.2. Isozyme Selective Inhibitors

4. Tools to Study the Role of Guanylyl Cyclases

4.1. Inhibitors of Soluble Guanylyl Cyclase

4.2. NO-donors

4.3. Activators of Soluble Guanylyl Cyclase

4.3.1. Heme-dependent sGC Activators

4.3.2. Heme-independent sGC Activators

4.4. Inhibitors of Particulate Guanylyl Cyclase

4.5. Activators of Particulate Guanylyl Cyclase

4.6. Antibodies

5. Modulation of cyclic Nucleotide Phosphodiesterases

5.1. Inhibitors of cGMP Phosphodiesterases (PDE5, PDE6 and PDE9)

5.2. Inhibitors of cAMP and cGMP phosphodiesterases (PDE1 and PDE2)

5.3. Antibodies

6. cGMP Membrane Transport (cGMP Efflux)

7. Modulation of Protein Kinase G

7.1. Inhibitors of PKG

7.2. Activators of PKG

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